An Overview of Candida spp Profile and Antimicrobial Susceptibility Test Profile of a Catheter-Associated Urinary Tract Infection (CAUTI) Patient at the Intensive Care Unit of Saiful Anwar Hospital in Malang, Indonesia

Penulis

  • Ronald Aprianto Parubak Institut Ilmu Kesehatan Bhakti Wiyata Penulis
  • Nurul Widyawati Bhakti Wiyata Institute of Health Science Penulis
  • Ida Rizqa Nuraini Bhakti Wiyata Institute of Health Science Penulis
  • Henny Tantono Bhakti Wiyata Institute of Health Science Penulis
  • Ketut Suhendro Bhakti Wiyata Institute of Health Science Penulis
  • Jeremy Sebastian Bhakti Wiyata Institute of Health Science Penulis
  • Rina Puspasari Suryana Bhakti Wiyata Institute of Health Science Penulis

Kata Kunci:

Candida spp, CAUTI, Intensive Care Unit

Abstrak

Background : Candida spp. is one of the pathogens causing an increase in CAUTI cases associated with catheter use in the ICU, with an incidence rate of 17.8%. This microorganism is considered the second major pathogen causing CAUTI cases in the ICU after Escherichia coli (Padawer et al., 2015).

Aims : To discover the candida profile of catheterized patients obtained during this year from ICU patients at General Hospital Dr.Saiful Anwar Malang and their antimicrobial susceptibility patterns.

Method : This study is a descriptive retrospective study using urine catheter specimens sent to the Microbiology Department of Dr. Saiful Anwar Hospital from January-December 2022. Fungi from culture were identified and susceptibility tests were performed using a VITEC 2 system standard and CLSI. The data is taken through WHONET software

Result and Discussion: The number of Candida spp isolated in this study was 41 from 283 positive samples isolated. Fungi that are isolated include Candida albicans 17 specimen (41.5%) and Candida non albicans 24 specimen (58.5%). Candida albicans are still sensitive to Fluconazole (100%), Voriconazole (100%) and Amphotericin B (100%). Candida non albicans are still sensitive to Fluconazole (87.5%), Voriconazole (100%) and Amphotericin B (100%)

Conclusion : Candida non albicans is the most common fungus isolated from specimens of CAUTI in January-December 2022 and the most sensitive antifungal for Candida spp are Voriconazole and Amphotericin B.

Referensi

Gajdács, M., Dóczi, I., Ábrók, M., Lázár, A., & Burián, K. (2019). Epidemiology of candiduria and Candida urinary tract infections in inpatients and outpatients: Results from a 10-year retrospective survey. Central European Journal of Urology, 72(2), 209–214.

https://doi.org/10.5173/CEJU.2019.1909

KNHSS Kuwait National Healthcare-associated Infections Surveillance System 1. (2015).

Magill, S. S., O’Leary, E., Janelle, S. J., Thompson, D. L., Dumyati, G., Nadle, J., Wilson, L. E., Kainer, M. A., Lynfield, R., Greissman, S., Ray, S. M., Beldavs, Z., Gross, C., Bamberg, W., Sievers, M., Concannon, C., Buhr, N., Warnke, L., Maloney, M., … Edwards, J. R. (2018). Changes in Prevalence of Health Care–Associated Infections in U.S. Hospitals. New England Journal of Medicine, 379(18), 1732–1744. https://doi.org/10.1056/NEJMOA1801550;CTYPE:STRING:JOURNAL

Padawer, D., Pastukh, N., Nitzan, O., Labay, K., Aharon, I., Brodsky, D., Glyatman, T., & Peretz, A. (2015). Catheter-associated candiduria: Risk factors, medical interventions, and antifungal susceptibility. American Journal of Infection Control, 43(7), e19–e22.

https://doi.org/10.1016/J.AJIC.2015.03.013

Rodrigues, C. F., Rodrigues, M. E., & Henriques, M. (2019). Candida sp. Infections in patients with diabetes mellitus. Journal of Clinical Medicine, 8(1). https://doi.org/10.3390/JCM8010076

Singh, Y., Karicheri, R., Nath, &, Singh, Y., Karicheri, R., & Nath, D. (2022). How to Cite: The burden of catheter associated urinary tract infection by candida Albicans and non Albicans with emphasis on biofilm formation and antifungal sensitivity pattern. International Journal of Health Sciences, 6(S2), 2356–2363. https://doi.org/10.53730/ijhs.v6nS2.5544

Diterbitkan

2026-03-05

Terbitan

Bagian

Research Article